Litcius/Paper detail

Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition

Moritz Hunkeler, Cyrus Y. Jin, W Michelle, Julie K. Monda, Daan Overwijn, Eric J. Bennett, Eric S. Fischer

2021Molecular Cell62 citationsDOIOpen Access PDF

Topics & Concepts

Ubiquitin ligaseBiologyDNA ligaseUbiquitinCell biologyGeneticsComputational biologyDNAGeneUbiquitin and proteasome pathwaysGenetics and Neurodevelopmental DisordersDNA Repair Mechanisms