Effect of UGT1A4, UGT2B7, UGT2B15, UGT2B17 and ABC1B polymorphisms on lamotrigine metabolism in Danish patients
Vaiva Petrenaite, Inger Öhman, Frederik Peter Thal Jantzen, Lena Ekström
Topics & Concepts
UGT2B7AlleleGenotypeInternal medicineLamotrigineSingle-nucleotide polymorphismCompound heterozygosityPolymorphism (computer science)EpilepsyEndocrinologyConcomitantCYP3A4MedicineGastroenterologyBiologyPharmacologyGeneticsMetabolismMicrosomeGenePsychiatryIn vitroCytochrome P450GlucuronidationEpilepsy research and treatmentDrug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism