Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems
Ilenia Grieco, Maicol Bissaro, Davide Benedetto Tiz, Daniel I. Pérez, Conception Perez, Ana Martı́nez, Sara Redenti, Elena Mariotto, Roberta Bortolozzi, Giampietro Viola, Giorgio Cozza, Giampiero Spalluto, Stefano Moro, Stephanie Federico
Topics & Concepts
ChemistryMoietyBicyclic moleculeStereochemistryKinaseMolecular modelProtein kinase APyrimidineTriazoleBiochemistryOrganic chemistryProtein Kinase Regulation and GTPase SignalingSynthesis and Characterization of Heterocyclic CompoundsSynthesis and Reactivity of Heterocycles