Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone
Jay K. Singh, Darren M. Hutt, Bradley D. Tait, Naihsuan C. Guy, Jeffrey C. Sivils, Nina R. Ortiz, Ashley N. Payan, Shravan Kumar Komaragiri, Jazzmin Jovonna Owens, David S. Culbertson, Laura J. Blair, Chad A. Dickey, Szu Yu Kuo, Dan Finley, H. Jane Dyson, Marc B. Cox, Jaideep Chaudhary, Jason E. Gestwicki, William E. Balch
Topics & Concepts
Hsp90LuciferaseChaperone (clinical)GeldanamycinCell biologyChemistryCo-chaperoneHsp90 inhibitorCancer researchComputational biologyBiochemistryBiologyTransfectionHeat shock proteinMedicineGenePathologyHeat shock proteins researchProtein Structure and DynamicsATP Synthase and ATPases Research