Intermolecular Carbophosphination of Alkynes with Phosphole Oxides via Ni−Al Bimetal‐Catalyzed C−P Bond Activation
Feng‐Ping Zhang, Rong‐Hua Wang, Jiang‐Fei Li, Hao Chen, Madala Hari Babu, Mengchun Ye
Abstract
Intermolecular carbophosphination reaction of alkynes or alkenes with unreactive C-P bonds remains an elusive challenge. Herein, we used a Ni-Al bimetallic catalyst to realize an intermolecular carbophosphination reaction of alkynes with 5-membered phosphole oxides, providing a series of 7-membered phosphepines in up to 94 % yield.
Topics & Concepts
Bimetallic stripBimetalIntermolecular forcePhospholeCatalysisYield (engineering)ChemistryPhotochemistryPolymer chemistryMedicinal chemistryMaterials scienceOrganic chemistryMoleculePhysical chemistryMetallurgyAsymmetric Hydrogenation and CatalysisOrganophosphorus compounds synthesisSulfur-Based Synthesis Techniques