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Enhanced Supervised Principal Component Analysis for Cancer Classification

Ghadeer Jasim Mohammed Mahdi, Bayda Atiya Kalaf, Mundher A. Khaleel

2021Iraqi Journal of Science17 citationsDOIOpen Access PDF

Abstract

In this paper, a new hybridization of supervised principal component analysis (SPCA) and stochastic gradient descent techniques is proposed, and called as SGD-SPCA, for real large datasets that have a small number of samples in high dimensional space. SGD-SPCA is proposed to become an important tool that can be used to diagnose and treat cancer accurately. When we have large datasets that require many parameters, SGD-SPCA is an excellent method, and it can easily update the parameters when a new observation shows up. Two cancer datasets are used, the first is for Leukemia and the second is for small round blue cell tumors. Also, simulation datasets are used to compare principal component analysis (PCA), SPCA, and SGD-SPCA. The results show that SGD-SPCA is more efficient than other existing methods.

Topics & Concepts

Principal component analysisComputer scienceStochastic gradient descentPattern recognition (psychology)Artificial intelligenceArtificial neural networkGene expression and cancer classificationAI in cancer detectionSpectroscopy and Chemometric Analyses
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