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Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma

Nicholas J. Haradhvala, Mark B. Leick, Katie Maurer, Satyen H. Gohil, Rebecca C. Larson, Ning Yao, Kathleen Gallagher, Katelin Katsis, Matthew J. Frigault, Jackson Southard, Shuqiang Li, Michael C. Kann, Harrison Silva, Max Jan, Kahn Rhrissorrakrai, Filippo Utro, Chaya Levovitz, Raquel A. Jacobs, Kara Slowik, Brian P. Danysh, Kenneth J. Livak, Laxmi Parida, Judith A. Ferry, Caron A. Jacobson, Catherine J. Wu, Gad Getz, Marcela V. Maus

2022Nature Medicine255 citationsDOIOpen Access PDF

Topics & Concepts

CD19Chimeric antigen receptorCD8Cytokine release syndromeLymphomaCell therapyPeripheral blood mononuclear cellCancer researchCAR T-cell therapyTranscriptomeImmunologyRefractory (planetary science)MedicineT cellCellAntigenBiologyImmune systemIn vitroGeneGeneticsGene expressionAstrobiologyCAR-T cell therapy researchImmune Cell Function and InteractionVirus-based gene therapy research
Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma | Litcius