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<i>Notes from the Field</i>: Surveillance for Multisystem Inflammatory Syndrome in Children — United States, 2023

Anna R Yousaf, Katherine Lindsey, Michael Wu, Ami B. Shah, Rebecca J. Free, Regina M. Simeone, Laura D. Zambrano, Angela P. Campbell, MIS-C Surveillance Authorship Group, S. Crook, Amy Clark, Tiffanie Fulton-Kennedy, Ashley Gent, Walaa M Elbedewy, Gabrielle Williams, Amanda Hartley, Kaleb Kitchens, Gillian Richardson, Marion Deming, Cole Burkholder, Jacob Reece, Tom Haupt, Amanda Mandi, Paige D’Heilly, Ayotola Falodun, C.J. Gil, Chelsea Campbell, Kimberly Carlson, Heather D. Reid, Deepam Thomas, Haytham Safi, Jacqueline Denning, Stacy Davidson, Maya Scullin, Allison Longenberger, Kelly Blythe, Xandy Peterson Pompa, Augustina Manuzak, Spencer Cunningham, Kate Cleavinger, Jannifer Anderson, Carmen B. Rodriguez, Lesley Roush

2024MMWR Morbidity and Mortality Weekly Report36 citationsDOIOpen Access PDF

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious condition typically occurring 2-6 weeks after SARS-CoV-2 infection and characterized by fever and multiorgan involvement (1,2).In May 2020, CDC created an MIS-C case definition and established a passive national surveillance system for voluntary case reporting by state and local health departments.*In 2022, CDC and the Council of State and Territorial Epidemiologists (CSTE) created a new surveillance case definition that went into effect on January 1, 2023 (3).Approximately 87% of cases reported using the 2020 case definition also meet the 2023 case definition.This report describes 2023 MIS-C cases and compares them with cases reported earlier in the COVID-19 pandemic.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)PandemicSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakPublic health surveillancePediatricsMedical emergencyEnvironmental healthFamily medicinePublic healthVirologyInternal medicinePathologyInfectious disease (medical specialty)OutbreakDiseaseKawasaki Disease and Coronary ComplicationsStreptococcal Infections and TreatmentsRespiratory viral infections research
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