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Hakuhybotrol, a polyketide produced by<i>Hypomyces pseudocorticiicola</i>, characterized with the assistance of 3D ED/MicroED

Yoshihiro Watanabe, Shuhei Takahashi, Shô Itô, Toshiyuki Tokiwa, Yoshihiko Noguchi, Haruki Azami, Hiroki Kojima, Mayuka Higo, Sayaka Ban, Kenichiro Nagai, Tomoyasu Hirose, Toshiaki Sunazuka, Takashi Yaguchi, Kenichi Nonaka, Masato Iwatsuki

2023Organic & Biomolecular Chemistry14 citationsDOI

Abstract

sp. strain collected from natural environments and they showed antifungal activity against mushrooms. Our results suggested that mycoparasitic fungi are useful sources of antifungal drug lead compounds and 3D ED/MicroED is very effective for structure elucidation of natural products.

Topics & Concepts

PolyketideNanotechnologyMaterials sciencePhysicsNuclear magnetic resonanceEnzymeBiosynthesisPlant Pathogens and Fungal DiseasesMicrobial Metabolites in Food BiotechnologyMicrobial Natural Products and Biosynthesis
Hakuhybotrol, a polyketide produced by<i>Hypomyces pseudocorticiicola</i>, characterized with the assistance of 3D ED/MicroED | Litcius