Electrochemical tandem trifluoromethylation of allylamines/formal (3 + 2)-cycloaddition for the rapid access to CF<sub>3</sub>-containing imidazolines and oxazolidines
Aurélie Claraz, Aurélie Djian, Géraldine Masson
Abstract
A straightforward and environmentally friendly synthesis of CF<sub>3</sub>-containing imidazolines and oxazolidines has been developed through an electrochemical three-component reaction among allylamines, the Langlois reagent, and nitrile or carbonyl compounds.
Topics & Concepts
ChemistryReagentNitrileTandemElectrochemistryCycloadditionTrifluoromethylationOrganic chemistryCombinatorial chemistryTrifluoromethylCatalysisElectrodeAlkylMaterials sciencePhysical chemistryComposite materialFluorine in Organic ChemistrySulfur-Based Synthesis TechniquesRadical Photochemical Reactions