Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors
Jan Møller, Ali Işbilir, Titiwat Sungkaworn, Brendan Osberg, Christos Karathanasis, Vikram Sunkara, Eugene O. Grushevskyi, Andreas Böck, Paolo Annibale, Mike Heilemann, Christof Schütte, Martin J. Lohse
Topics & Concepts
G protein-coupled receptorDAMGODimerAgonistReceptorChemistryInternalizationBiophysicsSignal transductionCell biologyBiochemistryOpioid receptorBiologyOrganic chemistryReceptor Mechanisms and SignalingMonoclonal and Polyclonal Antibodies ResearchNeuropeptides and Animal Physiology