Litcius/Paper detail

Open partial nephrectomy: current review

Ellen O’Connor, Brennan Timm, Nathan Lawrentschuk, Joseph Ischia

2020Translational Andrology and Urology42 citationsDOIOpen Access PDF

Abstract

Partial nephrectomy (PN) is increasingly considered the gold standard treatment for localized renal cell carcinomas (RCCs) where technically feasible. The advantage of nephron-sparing surgery lies in preservation of parenchyma and hence renal function. However, this advantage is counterbalanced with increased surgical risk. In recent years with the popularization of minimally invasive partial nephrectomy (laparoscopic and robotic), the contemporary role of open PN (OPN) has changed. OPN has several advantages, particularly in complex patients such as those with a solitary kidney, multi-focal tumors, and significant surgical history, as well as providing improved application of renoprotective measures. As such, it is a technique that remains relevant in current urology practice. In this article we discuss the evidence, indications, operative considerations and surgical technique, along with the role of OPN in contemporary nephron-sparing surgery.

Topics & Concepts

NephrectomyMedicineNephronRenal parenchymaRenal cell carcinomaGold standard (test)Renal functionUrologyKidneyOpen surgeryParenchymaSurgeryGeneral surgeryRadiologyInternal medicinePathologyRenal cell carcinoma treatmentRenal and related cancersBladder and Urothelial Cancer Treatments