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Discovery of pterostilbene analogs as novel NLRP3 inflammasome inhibitors for potential treatment of DSS-induced colitis in mice

Ban‐Feng Ruan, Minghui Rong, Zibei Ming, Ke Wang, Xiaohan Liu, Xiaohan Liu, Lijun Deng, Xingxing Zhang, Kun Xu, Cheng Shi, Tongfei Gao, Xinhua Liu, Xinhua Liu, Liuzeng Chen

2023Bioorganic Chemistry17 citationsDOI

Topics & Concepts

ChemistryPterostilbeneInflammasomeIn vivoPharmacologyIn vitroColitisCurcuminStructure–activity relationshipResveratrolBiochemistryImmunologyReceptorBiotechnologyMedicineBiologyInflammasome and immune disordersinterferon and immune responsesGout, Hyperuricemia, Uric Acid
Discovery of pterostilbene analogs as novel NLRP3 inflammasome inhibitors for potential treatment of DSS-induced colitis in mice | Litcius