Dualplex lateral flow assay for simultaneous scopolamine and “cannibal drug” detection based on receptor-gated mesoporous nanoparticles
Eva María Nieto Garrido, Estela Climent, M. Dolores Marcos, Félix Sancenón, Knut Rurack, Ramón Martínez‐Máñez
Abstract
-AChR resulting in pore opening and delivery of the entrapped rhodamine B reporter. Moreover, the material was incorporated into strips for lateral-flow assays coupled to smartphone readout, giving fast response time, good selectivity, and exceptional sensitivity. In an attempt to a mobile analytical test system for law enforcement services, we have also developed a dualplex lateral flow assay for SCP and 3,4-methylenedioxypyrovalerone (MDPV) also known as the so-called "cannibal drug".
Topics & Concepts
Rhodamine BNanoparticleChemistryMesoporous silicaNanotechnologyMaterials scienceMesoporous materialBiophysicsBiochemistryBiologyCatalysisPhotocatalysisAdvanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensorsMicrofluidic and Capillary Electrophoresis Applications