FAM111 protease activity undermines cellular fitness and is amplified by gain‐of‐function mutations in human disease
Saskia Hoffmann, Satyakrishna Pentakota, Andreas Mund, Peter Haahr, Fabian Coscia, Marta Gallo, Matthias Mann, Nicholas M. I. Taylor, Niels Mailand
Topics & Concepts
Gain of functionFunction (biology)BiologyProteaseDiseaseGeneticsMutationComputational biologyGeneEnzymeMedicineBiochemistryPathologyUbiquitin and proteasome pathwaysInvertebrate Immune Response MechanismsPeptidase Inhibition and Analysis