Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E
Ram Kumar, Mohammed Afsar, Nitin Khandelwal, Yogesh Chander, Thachamvally Riyesh, Ramesh Kumar Dedar, Baldev R. Gulati, Yash Pal, Sanjay Barua, Bhupendra Nath Tripathi, Tanweer Hussain, Naveen Kumar
Topics & Concepts
EIF4EEmetineCoronavirusViral replicationBiologyVirologyViral proteinInitiation factorMessenger RNAChemistryTranslation (biology)VirusPharmacologyBiochemistryMedicineCoronavirus disease 2019 (COVID-19)GenePathologyDiseaseInfectious disease (medical specialty)Protein Degradation and InhibitorsPeptidase Inhibition and AnalysisQuinazolinone synthesis and applications