Swainsonine inhibits autophagic degradation and causes cytotoxicity by reducing CTSD O-GlcNAcylation
Shuai Wang, Panpan Tan, Hongwei Wang, Jicang Wang, Cai Zhang, Hao Lu, Baoyu Zhao
Topics & Concepts
SwainsonineAutophagyLysosomeCathepsin DCell biologyCytotoxicityGlycosylationToxicityBiologyChemistryBiochemistryEnzymeIn vitroOrganic chemistryApoptosisGlycosylation and Glycoproteins ResearchCarbohydrate Chemistry and SynthesisGalectins and Cancer Biology