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A hydrogen sulfide-responsive prodrug for monitoring real-time release and improving therapeutic effects of anticancer drug SN-38

Kunshan Huang, Song Xie, Weijun Wang, Zai‐Sheng Wu, Juhong Wu, Lizhi Jiang, Juanjuan Chen, Jinyu Li

2022Sensors and Actuators B Chemical10 citationsDOI

Topics & Concepts

ProdrugIrinotecanSN-38Active metaboliteChemistryDrugPharmacologyCamptothecinIn vitroTherapeutic indexCancer cellToxicityCancer researchCombinatorial chemistryCancerMetaboliteMedicineBiochemistryInternal medicineOrganic chemistryColorectal cancerCancer therapeutics and mechanismsNanoplatforms for cancer theranosticsSynthesis and Biological Evaluation
A hydrogen sulfide-responsive prodrug for monitoring real-time release and improving therapeutic effects of anticancer drug SN-38 | Litcius