Biodegradable polymers with tertiary amines enhance mRNA delivery of lipid nanoparticles via improved endosomal escape
Feng Zhao, Bruno T. Luppi, Po‐Han Chao, J. Yang, Ying Zhang, Ran Feng, Vanessa Chan, Ramya Kannan, Songtao Dong, Athan T. Gogoulis, Leo Wang, Angel Lee, Zachary M. Hudson, Shyh‐Dar Li
Topics & Concepts
EndosomeTransfectionMessenger RNALuciferaseBiophysicsIntracellularCytotoxicityChemistryIn vivoMaterials scienceIn vitroBiologyBiochemistryGeneBiotechnologyRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesExtracellular vesicles in disease