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Methylmercury promotes oxidative stress and autophagy in rat cerebral cortex: Involvement of PI3K/AKT/mTOR or AMPK/TSC2/mTOR pathways and attenuation by N-acetyl-L-cysteine

Yanfeng Wei, Linlin Ni, Jingjing Pan, Xiaoyang Li, Yu Deng, Bin Xu, Tianyao Yang, Jingyi Sun, Wei Liu

2022Neurotoxicology and Teratology18 citationsDOI

Topics & Concepts

AutophagyPI3K/AKT/mTOR pathwayOxidative stressProtein kinase BChemistryNeurotoxicityAMPKNeuroprotectionTSC2PharmacologyEndocrinologyBiochemistrySignal transductionPhosphorylationBiologyApoptosisToxicityProtein kinase AOrganic chemistryHeavy Metal Exposure and ToxicityMercury impact and mitigation studiesHeme Oxygenase-1 and Carbon Monoxide
Methylmercury promotes oxidative stress and autophagy in rat cerebral cortex: Involvement of PI3K/AKT/mTOR or AMPK/TSC2/mTOR pathways and attenuation by N-acetyl-L-cysteine | Litcius