Phosphine-catalyzed sequential (2+3)/(2+4) annulation of γ-vinyl allenoates: access to the synthesis of chromeno[4,3-<i>b</i>]pyrroles
Xiaohu Li, You Huang
Abstract
]pyrrole derivatives that contain three contiguous stereogenic centers. The method gives a good yield, excellent chemoselectivity and diastereoselectivity under mild conditions.
Topics & Concepts
PhosphineAnnulationPyrroleCatalysisChemistryAldimineCombinatorial chemistryMedicinal chemistryOrganic chemistryAsymmetric Synthesis and CatalysisCatalytic C–H Functionalization MethodsSynthesis and Characterization of Pyrroles