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Ancestry may confound genetic machine learning: Candidate-gene prediction of opioid use disorder as an example

Alexander S. Hatoum, Frank R. Wendt, Marco Galimberti, Renato Polimanti, Benjamin M. Neale, Henry R. Kranzler, Joel Gelernter, Howard J. Edenberg, Arpana Agrawal

2021Drug and Alcohol Dependence20 citationsDOIOpen Access PDF

Topics & Concepts

Single-nucleotide polymorphismConfoundingCandidate geneGeneticsGenome-wide association studyMultiple comparisons problemGenetic genealogyHeritabilityBiologyAlleleArtificial intelligenceStatisticsGeneComputer scienceMedicineGenotypePopulationMathematicsEnvironmental healthGenetic Associations and EpidemiologyNeurotransmitter Receptor Influence on BehaviorOpioid Use Disorder Treatment
Ancestry may confound genetic machine learning: Candidate-gene prediction of opioid use disorder as an example | Litcius