Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney
Payal Kapur, Ming Gao, Hua Zhong, Suneetha Chintalapati, Midori Mitui, Spencer Barnes, Qinbo Zhou, Jeffrey Miyata, Deyssy Carrillo, Venkat S. Malladi, Dinesh Rakheja, Iván Pedrosa, Lin Xu, Lisa N. Kinch, James Brugarolas
Topics & Concepts
EosinophilicPathologyTSC1CD117BiologyPI3K/AKT/mTOR pathwayTuberous sclerosisChromophobe cellmTORC1RHEBCancer researchGermline mutationClear cellRenal cell carcinomaMutationMedicineGeneticsCD34GeneStem cellApoptosisRenal cell carcinoma treatmentRenal and related cancersCancer Genomics and Diagnostics