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Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation

Ying Zhang, Pourya Naderi Yeganeh, Haiwei Zhang, Simon Yuan Wang, Zhouyihan Li, Bowen Gu, Dian-Jang Lee, Zhibin Zhang, Athanasios Ploumakis, Ming Shi, Hao Wu, Eric Lieberman Greer, Winston Hide, Judy Lieberman

2024Nature Immunology50 citationsDOI

Topics & Concepts

Innate immune systemDNA methylationImmunityBiologyAcquired immune systemDNAMethylationEpigeneticsCancer researchCell biologyImmunologyGeneticsGeneImmune systemGene expressionHIV Research and TreatmentEpigenetics and DNA MethylationCRISPR and Genetic Engineering
Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation | Litcius