Hydroxysafflor yellow A inhibits hypoxia/reoxygenation-induced cardiomyocyte injury via regulating the AMPK/NLRP3 inflammasome pathway
Jingxue Ye, Min Wang, Ruiying Wang, Haitao Liu, Yaodong Qi, Jian-Hua Fu, Qiong Zhang, Bengang Zhang, Xiaobo Sun
Topics & Concepts
InflammasomeAMPKAutophagyPharmacologyChemistryReperfusion injuryHypoxia (environmental)Downregulation and upregulationCaspase 1ApoptosisCell biologyIschemiaMedicineReceptorBiochemistryBiologyProtein kinase AInternal medicinePhosphorylationOrganic chemistryOxygenGeneInflammasome and immune disordersAutophagy in Disease and TherapyHeme Oxygenase-1 and Carbon Monoxide