Design and synthesis of novel Flavone-based histone deacetylase inhibitors antagonizing activation of STAT3 in breast cancer
Mingming Wei, Maodun Xie, Zhen Zhang, Yujiao Wei, Juan Zhang, Hongli Pan, Benlong Li, Jingjing Wang, Jingjing Wang, Yang Song, Chuangke Chong, Rui Zhao, Jiefu Wang, Jiefu Wang, Yu Li, Guang Yang, Cheng Yang
Topics & Concepts
Histone deacetylaseChemistryCancer researchAcetylationCancer cellBreast cancerCancerSTAT3HDAC1ApoptosisIn vivoPharmacologyCell cycleHistoneBiochemistryBiologyMedicineInternal medicineBiotechnologyGeneHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsSynthesis and biological activity