Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome
Yuejun Wang, Xicheng Zhang, Chi Keung Lam, Hongchao Guo, Cheng Wang, Sai Zhang, Joseph C. Wu, M Snyder, Jingjing Li
Topics & Concepts
Hypoplastic left heart syndromeInteractomeBiologyTranscriptomeGene regulatory networkExome sequencingComputational biologyHeart diseaseBioinformaticsGeneGeneticsMutationMedicineInternal medicineGene expressionCongenital heart defects researchCongenital Heart Disease StudiesSingle-cell and spatial transcriptomics