Bioinspired bimodal micro-nanofibrous scaffolds promote the tenogenic differentiation of tendon stem/progenitor cells for achilles tendon regeneration
Zhiwei Yin, Lu Sun, Liyang Shi, Hemin Nie, Jianwu Dai, Can Zhang
Abstract
implantation study confirmed that micro-nanofibrous scaffolds promoted the structural and mechanical properties of the regenerated Achilles tendon. Overall, our study shows that the bimodal micro-nanofibrous scaffold developed here presents a promising potential to improve the outcomes of tendon tissue engineering.
Topics & Concepts
ScaffoldNanotopographyTendonAchilles tendonProgenitor cellRegeneration (biology)NanofiberBiomedical engineeringMesenchymal stem cellStem cellMaterials scienceChemistryCell biologyAnatomyNanotechnologyBiologyMedicineTendon Structure and TreatmentShoulder Injury and TreatmentSports injuries and prevention