Evaluating orthogonality between ion-pair reversed phase, anion exchange, and hydrophilic interaction liquid chromatography for the separation of synthetic oligonucleotides
Matthew J. Sorensen, Mellie June Paulines, Todd D. Maloney
Topics & Concepts
ChemistryHydrophilic interaction chromatographySelectivityChromatographyElutionReagentOligonucleotideResolution (logic)NucleobaseReversed-phase chromatographyHigh-performance liquid chromatographyOrganic chemistryDNACatalysisArtificial intelligenceComputer scienceBiochemistryAnalytical Chemistry and ChromatographyMicrofluidic and Capillary Electrophoresis ApplicationsRNA and protein synthesis mechanisms