Guanine nucleotide exchange factors for Rho GTPases (RhoGEFs) as oncogenic effectors and strategic therapeutic targets in metastatic cancer
Rodolfo Daniel Cervantes‐Villagrana, Irving García‐Jiménez, José Vázquez‐Prado
Topics & Concepts
Guanine nucleotide exchange factorGTPaseCell biologyCytoskeletonBiologyStromal cellEffectorTumor microenvironmentCancer cellRAC1Actin cytoskeletonCancerSignal transductionCancer researchCellBiochemistryGeneticsProtein Kinase Regulation and GTPase SignalingMicrotubule and mitosis dynamicsCellular Mechanics and Interactions