Visualizing intracellular particles and precise control of drug release using an emissive hydrazone photochrome
Xing Guo, Baihao Shao, Shaobing Zhou, Ivan Aprahamian, Zi Chen
Abstract
A light-triggered NP drug delivery system was assembled using amphiphilic copolymers modified with fluorescent and bistable hydrazone photoswitches, where switching results in NP expansion and emission quenching, which was used to assess the amount of drug released.
Topics & Concepts
HydrazoneIntracellularChemistryDrugCombinatorial chemistryPharmacologyStereochemistryBiochemistryMedicinePhotochromic and Fluorescence Chemistrybioluminescence and chemiluminescence researchInnovative Microfluidic and Catalytic Techniques Innovation