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Rapid discovery of cyclic peptide protein aggregation inhibitors by continuous selection

Linwei Yang, Jingwei Zhang, James S. Andon, Lingjun Li, Tina Wang

2025Nature Chemical Biology14 citationsDOIOpen Access PDF

Topics & Concepts

Cyclic peptideSelection (genetic algorithm)PeptideComputational biologyDrug discoveryChemistryBiochemistryBiologyComputer scienceArtificial intelligenceChemical Synthesis and AnalysisUbiquitin and proteasome pathwaysGlycosylation and Glycoproteins Research
Rapid discovery of cyclic peptide protein aggregation inhibitors by continuous selection | Litcius