Oral genistein-loaded phytosomes with enhanced hepatic uptake, residence and improved therapeutic efficacy against hepatocellular carcinoma
Ibrahim A. Komeil, Wessam M. El-Refaie, Mennatallah A. Gowayed, Samar O. El-Ganainy, Samar El Achy, Kristiina M. Huttunen, Ossama Y. Abdallah
Topics & Concepts
GenisteinBioavailabilityHepatocellular carcinomaIn vivoCytotoxicityPharmacologyOral administrationChemistryPharmacokineticsFirst pass effectLiver cancerMetabolismCancer researchIn vitroMedicineInternal medicineBiochemistryBiologyBiotechnologySilymarin and Mushroom PoisoningSynthesis and bioactivity of alkaloidsCurcumin's Biomedical Applications