Modulation of emission and singlet oxygen photosensitisation in live cells utilising bioorthogonal phosphorogenic probes and protein tag technology
Peter Kam‐Keung Leung, Kenneth Kam‐Wing Lo
Abstract
We developed a strategy to exploit the bioorthogonal reactivity and phosphorogenic property of iridium(<sc>iii</sc>) polypyridine nitrone complexes and SNAP-tag protein for the modulation of emission and single oxygen photosensitisation in live cells.
Topics & Concepts
Bioorthogonal chemistrySinglet oxygenChemistryCombinatorial chemistryIridiumReactivity (psychology)NitroneClick chemistryPhotochemistryOxygenBiochemistryCatalysisOrganic chemistryCycloadditionMedicineAlternative medicinePathologyClick Chemistry and ApplicationsNanoplatforms for cancer theranosticsPhotodynamic Therapy Research Studies