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AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop

Xiaojuan Han, Tianying Zhang, Xiaohua Zhang, Ruisan Zhang, Kejing Lao, Yajing Mi, Xingchun Gou

2020Mechanisms of Ageing and Development26 citationsDOI

Topics & Concepts

SenescenceAMPKCell biologyOxidative stressSTAT3NF-κBProinflammatory cytokineAMP-activated protein kinaseBiologySignal transductionProtein kinase AInflammationChemistryKinaseImmunologyEndocrinologyTelomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model OrganismsNeutrophil, Myeloperoxidase and Oxidative Mechanisms
AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop | Litcius