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The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

Jun Fang, Hideaki Nakamura, Hiroshi Maeda

2010Advanced Drug Delivery Reviews3,505 citationsDOI

Topics & Concepts

ExtravasationDrug deliveryVascular permeabilityDrugPharmacologyAngiogenesisMedicineElectron paramagnetic resonanceVasodilationBlood vesselChemistryCancer researchPathologyInternal medicineNuclear magnetic resonancePhysicsOrganic chemistryNanoplatforms for cancer theranosticsLanthanide and Transition Metal ComplexesMetal complexes synthesis and properties
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect | Litcius