Novel indole-pyrazole hybrids as potential tubulin-targeting agents; Synthesis, antiproliferative evaluation, and molecular modeling studies
Mohammed Hawash, Sezen Güntekin Ergün, Deniz Kahraman, Abdurrahman Olğaç, Ernest Hamel, Rengül Çetin-Atalay, Sultan Nacak Baytaş
Topics & Concepts
ChemistryIndole testPyrazoleTubulinHybridCombinatorial chemistryComputational biologyStereochemistryCell biologyMicrotubuleBotanyBiologySynthesis and biological activityMulticomponent Synthesis of HeterocyclesBioactive Compounds and Antitumor Agents