High-fidelity intracellular imaging of multiple miRNAs <i>via</i> stimulus-responsive nanocarriers and catalytic hairpin assembly
Hongyan Zhang, Wendong Liu, Fanghua Zhang, Zhihan Wu, Haijun Lu, Zhe Hao, Yu Liu, Xiyan Li, Ruizhong Zhang, Libing Zhang
Abstract
released the DNA cargos, activating the CHA circuits and recovering the fluorescence. This approach offers a reliable sensing performance with highly selective cell-identification capacity, positioning it as a pivotal tool for imaging multiple biomarkers in living cells.
Topics & Concepts
NanocarriersmicroRNAIntracellularStimulus (psychology)FidelityHigh fidelityNanotechnologyBiophysicsChemistryCell biologyMaterials scienceBiologyComputer sciencePsychologyPhysicsNanoparticleBiochemistryTelecommunicationsGenePsychotherapistAcousticsAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryNanoplatforms for cancer theranostics