ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins
Michael J. McKenna, Benjamin M. Adams, Vincent B. Chu, João A. Paulo, Sichen Shao
Topics & Concepts
Endoplasmic-reticulum-associated protein degradationEndoplasmic reticulumBiologyCell biologySignal peptideProtein foldingMembrane proteinTransmembrane proteinProtein targetingSec61CytosolAAA proteinsBiochemistryUnfolded protein responseTransloconPeptide sequenceATPaseMembraneReceptorGeneEnzymeEndoplasmic Reticulum Stress and DiseaseBacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms