Catch and release strategy of matrix metalloprotease aptamers <i>via</i> thiol–disulfide exchange reaction on a graphene based electrochemical sensor
Vladyslav Mishyn, Merve Aslan, Adrien Hugo, Teresa Rodrigues, H. Happy, Rana Sanyal, Wolfgang Knoll, Florence Baudoux, Vincent Bouchiat, Rostyslav Bilyy, Rabah Boukherroub, Amitav Sanyal, Sabine Szunerits
Abstract
Matrix metalloproteases (MMP) sensing in wound fluids using 1-pyrene pyridyl disulphide modified GFETs in a catch-release approach is discussed.
Topics & Concepts
GrapheneAptamerThiolPyreneMatrix (chemical analysis)ElectrochemistryChemistryMolybdenum disulfideCombinatorial chemistryDisulfide bondBiosensorNanotechnologyChemical engineeringMaterials scienceOrganic chemistryBiochemistryChromatographyElectrodeEngineeringGeneticsBiologyPhysical chemistryAdvanced biosensing and bioanalysis techniquesConducting polymers and applicationsElectrochemical sensors and biosensors