Targeted delivery of capecitabine to colon cancer cells using nano polymeric micelles based on beta cyclodextrin
Hossein Ameli, Nina Alizadeh
Abstract
drug release exemplified that the micelles were pH-sensitive, this action was shown that firstly the drug release was done perfectly targeted and under control and secondly the drug has been released above 80% inside the colon.
Topics & Concepts
CopolymerCapecitabineMicelleCyclodextrinFourier transform infrared spectroscopyDrug deliveryDrugChemistryNuclear chemistryControlled releaseNanotechnologyMaterials scienceChemical engineeringColorectal cancerOrganic chemistryPharmacologyCancerPolymerAqueous solutionMedicineInternal medicineEngineeringNanoparticle-Based Drug DeliveryDrug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms