Relationship Between Helicobacter pylori Infection and Arteriosclerosis
Yoshitaka Furuto, Mariko Kawamura, Jumpei Yamashita, Takahiro Yoshikawa, Akio Namikawa, Rei Isshiki, Hiroko Takahashi, Yuko Shibuya
Abstract
Abstract: It is reported that Helicobacter pylori ( H. pylori ) infection may be linked to non-digestive tract diseases, such as arteriosclerosis including dyslipidemia, diabetes, obesity, hypertension, and cardiovascular disease. Therefore, we reviewed recent studies available in PubMed dealing with the mechanisms of arteriosclerosis due to H. pylori infection and the effects of H. pylori eradication. Conventional studies suggested that H. pylori infection may increase the risk of arteriosclerosis. A large interventional study is required to clarify the causal relationships and the effects of bacterial eradication. Keywords: Helicobacter pylori infection, arteriosclerosis, hypertension