Intramolecular Heck Reaction in Total Synthesis of Natural Products: An Update
Debobrata Paul, Subhendu Das, Sanu Saha, Himangshu Sharma, Rajib Kumar Goswami
Abstract
Abstract This review highlights the application of intramolecular Heck reaction in total synthesis of natural products which were successfully synthesized in recent years (2013 to 2019). Heck cyclization was used as one of the strategic steps for constructions of wide variety of cyclic scaffolds essential for preparation of different natural products.
Topics & Concepts
Heck reactionIntramolecular forceChemistryTotal synthesisOrganic chemistryCombinatorial chemistryPalladiumCatalysisChemical synthesis and alkaloidsCatalytic Cross-Coupling ReactionsAdvanced Synthetic Organic Chemistry