The Role of microRNA in Pancreatic Cancer
Beata Smolarz, Adam Durczyński, Hanna Romanowicz, Piotr Hogendorf
Abstract
MicroRNAs (miRNAs) are small ribonucleic acid molecules that play a key role in regulating gene expression. The increasing number of studies undertaken on the functioning of microRNAs in the tumor formation clearly indicates their important potential in oncological therapy. Pancreatic cancer is one of the deadliest cancers. The expression of miRNAs released into the bloodstream appears to be a good indicator of progression and evaluation of the aggressiveness of pancreatic cancer, as indicated by studies. The work reviewed the latest literature on the importance of miRNAs for pancreatic cancer development.
Topics & Concepts
microRNAPancreatic cancerCancerBiologyCancer researchBioinformaticsGene expressionGeneInternal medicineMedicineGeneticsMicroRNA in disease regulationCircular RNAs in diseasesExtracellular vesicles in disease