Molecularly Engineering Triptolide with Aptamers for High Specificity and Cytotoxicity for Triple-Negative Breast Cancer
Jiaxuan He, Tianhuan Peng, Yongbo Peng, Lili Ai, Zhengyu Deng, Xue‐Qiang Wang, Weihong Tan
Abstract
anti-TNBC efficacy and negligible side effects toward healthy organs.
Topics & Concepts
Triple-negative breast cancerTriptolideConjugateCytotoxicityAptamerChemistryBreast cancerCancer researchIn vivoTargeted therapyCancerPharmacologyInternal medicineIn vitroMedicineMolecular biologyApoptosisBiologyBiochemistryBiotechnologyMathematicsMathematical analysisRNA Interference and Gene DeliveryNatural Compounds in Disease TreatmentAdvanced biosensing and bioanalysis techniques