A human three-dimensional neural-perivascular ‘assembloid’ promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology
Lu Wang, David Sievert, Alex E. Clark, Sangmoon Lee, Hannah G. Federman, Benjamin D. Gastfriend, Eric V. Shusta, Sean P. Palecek, Aaron F. Carlin, Joseph G. Gleeson
Topics & Concepts
NeuropathologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Neuroscience2019-20 coronavirus outbreakHuman brainVirologyMedicinePathologyBiologyDiseaseOutbreakInfectious disease (medical specialty)Long-Term Effects of COVID-19Cerebrospinal fluid and hydrocephalusCOVID-19 diagnosis using AI