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The impact of <scp>COVID</scp>‐19 on head and neck cancer diagnosis and disease extent

Kimberley L. Kiong, Edward M. Diaz, Neil D. Gross, Eduardo M. Diaz, Ehab Y. Hanna

2021Head & Neck76 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Due to COVID-19, diagnostic delays and a surge of advanced head and neck cancer (HNC) is anticipated. We hereby evaluate patient and tumor characteristics before and during the early COVID-19 period. METHODS: Retrospective review of patients with HNC presented at a multidisciplinary tumor conference from May 14, 2020 to June 18, 2020 was performed and compared to a similar 6-week period a year before. Demographics, time to diagnosis, and tumor characteristics were analyzed. RESULTS: There was a 25% reduction in newly diagnosed malignancies. Groups were similar in baseline characteristics, duration of symptoms, and time to diagnosis. However, median primary tumor size was significantly larger (p = 0.042) and T stage more advanced for mucosal subsites (p = 0.025) in the COVID-19 group. CONCLUSION: Our findings suggest increased tumor burden in patients with HNC presenting during the pandemic, despite a similar time to diagnosis. This may become more pronounced as the pandemic duration is extended.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)DemographicsHead and neck cancerPandemicHead and neckDiseaseRetrospective cohort studySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CancerInternal medicineStage (stratigraphy)Tumor stage2019-20 coronavirus outbreakOncologyPediatricsSurgeryPathologyInfectious disease (medical specialty)DemographyOutbreakSociologyBiologyPaleontologyCOVID-19 and healthcare impactsHead and Neck Cancer StudiesInfection Control and Ventilation