Mechanochemical approaches towards the <i>in situ</i> confinement of 5-FU anti-cancer drug within MIL-100 (Fe) metal–organic framework
Barbara Souza, Jin‐Chong Tan
Abstract
Low-cost mechanochemistry methods for <italic>in situ</italic> confinement of “guest” drug molecules into a “host” metal–organic framework to yield nanoscale guest@host drug delivery systems.
Topics & Concepts
MechanochemistryNanotechnologyMetal-organic frameworkDrug deliveryHost (biology)Materials scienceNanoscopic scaleYield (engineering)MoleculeMetalIn situDrugCombinatorial chemistryChemistryOrganic chemistryMetallurgyMedicinePharmacologyBiologyEcologyAdsorptionMetal-Organic Frameworks: Synthesis and ApplicationsCrystallography and molecular interactionsX-ray Diffraction in Crystallography