Litcius/Paper detail

The role of GLP-1 receptor agonists in managing type 2 diabetes

Noura Nachawi, Pratibha PR Rao, Vinni Makin

2022Cleveland Clinic Journal of Medicine43 citationsDOIOpen Access PDF

Abstract

Glucagon-like peptide-1 (GLP-1) receptor agonists improve glycemic control in patients with type 2 diabetes mellitus, have cardioprotective and renoprotective effects, and do not cause weight gain or significant hypoglycemia. In fact, they have been found to be effective for weight loss in patients with obesity with and without diabetes. They are now the preferred drugs to add to the regimen when oral metformin by itself is not enough to meet the patient's hemoglobin A1c goal.

Topics & Concepts

MedicineMetforminGlycemicHypoglycemiaType 2 diabetesWeight lossDiabetes mellitusGlucagon-like peptide 1 receptorType 2 Diabetes MellitusInternal medicineGlucagon-like peptide-1EndocrinologyAgonistRegimenPharmacologyObesityReceptorDiabetes Treatment and ManagementDiet and metabolism studiesPharmacology and Obesity Treatment