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BCR::ABL1 Proteolysis-targeting chimeras (PROTACs): The new frontier in the treatment of Ph+ leukemias?

Nataly Cruz-Rodríguez, Hua Tang, Benjamin Bateman, Weiping Tang, Michael W. Deininger

2024Leukemia16 citationsDOIOpen Access PDF

Topics & Concepts

Tyrosine kinaseCancer researchLeukemiaMedicineMyeloid leukemiaUbiquitin ligaseImmunologyBiologyUbiquitinInternal medicineGeneticsReceptorGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsChronic Myeloid Leukemia Treatments
BCR::ABL1 Proteolysis-targeting chimeras (PROTACs): The new frontier in the treatment of Ph+ leukemias? | Litcius